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Both wild-type and knockout mice were divided into eight and four groups, respectively, and maintained under a 12:12 h lightdark cycle in irradiated poplar litter

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The factors that trigger the development of valve myxomatous degeneration are still unknown, but aberrant TGFB signaling appears to initiate and perpetuate the valve pathology characteristic of this disease in the dog." In his May 2022 article summarizing the role of TGF-B in the onset and progression of MVD, Dr